Immuno-Oncology
Explore immune response with spatial biology insights
The tumor microenvironment (TME) represents a complex landscape of cancerous, normal and immune cells within diverse cellular neighborhoods and niches. Understanding the spatial dynamics of cells and tissues and their interplay is crucial for comprehending and treating cancer and requires advanced imaging technologies capable of capturing multiparametric spatial data at high throughput.
Now, researchers can interrogate the TME with the fastest, most comprehensive approach by using new whole slide imaging modes for Imaging Mass Cytometry™ (IMC™), enabling high-multiplex imaging to advance immuno-oncology studies.
Standardized panels to easily interpret tissue heterogeneity
Quickly develop a deep understanding of cancer-related processes in the tumor microenvironment with human- and mouse-specific panels that enable detection of tumor-infiltrating lymphocytes, immune activation and tissue architecture.
New Products
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New in IMC for immuno-oncology
Reveal Heterogeneity of Tumors With Whole Slide Imaging
This application note highlights the capability of IMC whole slide imaging together with ready-to-go human immuno-oncology IMC panels to provide streamlined and extensive evaluation of the human tumor microenvironment. This fast and comprehensive approach means researchers can quickly capture biological insights across the whole tumor at the single-cell level.
New imaging modes in immuno-oncology applications
View a lookbook showcasing translational and clinical applications of multiplexed tissue analysis of tumor samples.
Co-detection of RNA and protein
Deciphering the spatial arrangement of cell types within the TME could be crucial in empowering the next immuno-oncology breakthroughs. Co-detection of RNA and protein using IMC is a novel approach that enables interrogation of gene expression specific to a cell type of interest and identification of the source of a secreted protein, all in the context of the spatial landscape.
IMC Trending Topics in Immuno-Oncology
This article covers the latest research and past publications using IMC to explore the tumor-immune landscape, biomarker discovery and methods associated with therapeutics development.
Immuno-oncology e-book
In this e-book, two articles selected from the Drug Target Review highlight findings that researchers believe could be used to enhance immunotherapies. This is supplemented with a short Expert View article on using IMC to accelerate success in cancer immunotherapy development.
Jana Fischer, PhD
Co-Founder and CEO, Navignostics
Using spatial biology to navigate treatments for each cancer patient
Hear how the team at Navignostics is translating spatial insights into the clinic by using single-cell spatial data to generate actionable reports on tumor features within 72 hours of sample receipt, revolutionizing treatment decisions for each cancer patient.
Customer Stories
Learn more about how our customers are leveraging Standard BioTools™ technology
Jana Fischer, PhD
Paving a new road for spatial biology in precision medicine
Hartland Jackson, PhD
Entering an era of new biology
Corinne Ramos, PhD, MBA
Advancing drug development with molecular imaging
Yongpan Yan, PhD
An approach that combines molecular biology, immunology and cell biology tools to uniquely
Posters
Poster: Reveal the Heterogeneity of Glioblastoma and Other Tumors Using High-Plex IMC Empowered by Whole Slide Imaging Modes
Poster: Novel Whole Slide Imaging Modes for Imaging Mass Cytometry Reveal Cellular and Structural Composition of Mouse Glioblastoma
Poster: Novel Whole Slide Imaging Modes for Imaging Mass Cytometry Unveil Extensive Cellular Heterogeneity in Human Gliomas
Poster: Next Generation of Spatial Biology: High-Thoroughput Multiplexed Imaging Mass Cytometry With Whole Slide Modes
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