IMC Technical Note

Download Co-Detection of RNA and Protein to Explore Tumor-Immune Interactions Utilizing RNAscope With Imaging Mass Cytometry

Although cellular identity can easily be deciphered through detection of protein targets, knowledge of the cell’s transcriptome improves understanding of cellular function and activation state.

This technical note provides a workflow to achieve RNA and protein co-detection data in IMC experiments. Using highly sensitive and specific RNAscope™ technology for RNA detection with the multiplexing capability of IMC, you can visualize key RNA and protein markers in the same formalin-fixed, paraffin-embedded samples.

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