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High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance

02/07/2024
Yu-Hwa Huang, Charles H. Yoon, Amit Gandhi, Thomas Hanley, Carlos Castrillon, Yasuyuki Kondo, Xi Lin, Walter Kim, Chao Yang, Amine Driouchi, Michael Carroll, Scott D. Gray-Owen, Duane R. Wes
commun med
https://www.nature.com/articles/s43856-024-00525-8
Immunology

γδ T cells in human colon adenocarcinomas comprise mainly Vδ1, Vδ2, and Vδ3 cells with distinct phenotype and function

02/07/2024
William Rodin, Louis Szeponik, Tsvetanka Rangelova, Firaol Tamiru Kebede, Tobias Österlund, Patrik Sundström, Stephen Hogg, Yvonne Wettergren, Antonio Cosma, Anders Ståhlberg, Elinor Bexe Li
Can Immunol, Immunother
https://link.springer.com/article/10.1007/s00262-024-03758-7
Ag-Genomics

Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer

28/06/2024
Linda Bojmar, Constantinos P. Zambirinis, Jonathan M. Hernandez, Jayasree Chakraborty, Lee Shaashua, Junbum Kim, Kofi Ennu Johnson, Samer Hanna, Gokce Askan, Jonas Burman, Hiranmayi Ravichan
Nat Med
https://www.nature.com/articles/s41591-024-03075-7

Probabilistic pathway-based multimodal factor analysis

28/06/2024
Alexander Immer, Stefan G Stark, Francis Jacob, Ximena Bonilla, Tinu Thomas, André Kahles, Sandra Goetze, Emanuela S Milani, Bernd Wollscheid, The Tumor Profiler Consortium, Gunnar Rätsch, K
Bioinformatics
https://academic.oup.com/bioinformatics/article/40/Supplement_1/i189/7700877?login=false
Immunology

Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome

28/06/2024
Micah G. Donovan, Neetha P. Eduthan, Keith P. Smith, Eleanor C. Britton, Hannah R. Lyford, Paula Araya, Ross E. Granrath, Katherine A. Waugh, Belinda Enriquez Estrada, Angela L. Rachubinski,
Nat Commun
https://www.nature.com/articles/s41467-024-49781-1

CD161+CD127+CD8+ T cell subsets can predict the efficacy of anti-PD-1 immunotherapy in non-small cell lung cancer with diabetes mellitus

27/06/2024
Jingjing QuORCID Icon,Yuekang Li,Binggen Wu,Qian Shen,Lijun Chen,Wenjia Sun,Bo Wang,Lixiong Ying,Li Wu,Hong Zhou,Jianya Zhou &Jianying Zhou
Oncoimmunol
https://www.tandfonline.com/doi/full/10.1080/2162402X.2024.2371575
Copy Number Variation

Characterising plasmacytoid and myeloid AXL+ SIGLEC-6+ dendritic cell functions and their interactions with HIV

26/06/2024
Freja A. Warner van Dijk,Orion Tong,Thomas R. O’Neil,Kirstie M. Bertram,Kevin Hu,Heeva Baharlou,Erica E. Vine,Kate Jenns,Martijn P. Gosselink,James W. Toh,Tim Papadopoulos,Laith Barnouti,Gre
PLOS Pathogens
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012351
Biomarker Discovery

Associations of amyloid-β oligomers and plaques with neuropathology in the AppNL-G-F mouse

25/06/2024
Jiabin Tang, Helen Huang, Robert C J Muirhead, Yue Zhou, Junheng Li, John DeFelice, Maksym V Kopanitsa, Lutgarde Serneels, Karen Davey, Bension S Tilley, Steve Gentleman, Paul M Matthews
Brain Communications
https://academic.oup.com/braincomms/advance-article/doi/10.1093/braincomms/fcae218/7698916?login=false
Cell Segmentation

Spatial proteomic landscape of primary and relapsed hepatocellular carcinoma reveals immune escape characteristics in early relapse

20/06/2024
Yang M, Song X, Zhang F, Li M, Chang W, Wang Z, Li M, Shan H, Li D.
Hepatology
https://journals.lww.com/hep/abstract/9900/spatial_proteomic_landscape_of_primary_and.923.aspx
Digital Pathology

Activated HLA-DR+CD38+ Effector Th1/17 Cells Distinguish Crohn’s Disease-associated Perianal Fistulas from Cryptoglandular Fistulas

22/05/2024
Ouboter LF, Lindelauf C, Jiang Q, Schreurs M, Abdelaal TR, Luk SJ, Barnhoorn MC, Hueting WE, Han-Geurts IJ, Peeters KCMJ, Holman FA, Koning F, van der Meulen-de Jong AE, Pascutti MF.
Inflammatory Bowel Diseases
https://academic.oup.com/ibdjournal/advance-article/doi/10.1093/ibd/izae103/7679971?login=false
Biomarker Discovery