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Single-Cell Proteomics Services

Granular functional profiling

Accelerate translational research and drug development with high‑content proteomics powered by mass cytometry. CyTOF technology delivers integrated immune and functional insight at single‑cell resolution – simultaneously measuring cell surface markers, intracellular signaling proteins and cytokines – to inform mechanism of action, biomarker strategy and therapeutic decision‑making.

CyTOF systems deliver unparalleled coverage and resolution

  • Analyze 50-plus markers, both cell type and function, from a single panel
  • Access 40-plus modular panels and 800-plus labeled antibodies
  • Compatible with cryopreserved PBMC, whole blood and standard reagents
  • 21 CFR Part 11 compliance available

Data analysis that captures breadth and depth

SBI Lab Services provides you with raw FCS files and advanced data analysis for publication-ready results.

 

t-SNE map showing overlay of 25
clusters identified in the dataset
based on differential expression of
surface and intracellular markers(1)

 

 

Heat map depicting hierarchal clustering of phenotypic and functional markers across the PhenoGraph cellular clusters identified (color matched to the t-SNE map)

 

 

Example of immuno-functional diversity observed:
PhenoGraph cluster #7 is highlighted on the t-SNE map

Superior quality for outsourcing

High‑quality data regardless of sample preparation

 

Consistency across different sample collection methods:

  • Fresh-stained
  • Stain-preserved
  • Preserve-stained

 

 

Up to 72 hours of reliable results with stabilized whole blood(2)

Custom dry reagents

LyoMax™ CyTOF Panels

  • Fully tailored lyophilized antibody panels
  • Transform your liquid antibody panels into a dried-down pellet
  • Standardized immune profiling for large-scale, longitudinal and multi-site studies

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Data references

  1. A 20-Marker Core Immune Flow Cytometry Panel Optimized for Flexible Whole Blood Preservation Workflows Application Note
    (FLDM-01322).
  2. Awong, G. et al. SITC poster (2023)