CyTOF™ XT PRO
The widest immune coverage - at faster speeds
Identify novel disease drivers and design better therapies
CyTOF™ XT PRO
The widest immune coverage - at faster speeds
Identify novel disease drivers and design better therapies
CyTOF XT PRO is the next evolution in mass cytometry
Analyzing immune responses at a scale not possible with other methods, the CyTOF XT PRO system facilitates large immunophenotyping initiatives while meeting regulatory needs for GLP labs. This advanced system brings ease and accuracy to large-scale clinical trials by combining proven reproducibility with enhanced throughput capabilities and 21 CFR Part 11 compliance-enabling software.
The CyTOF XT PRO system takes proven mass cytometry to speeds of up to 4x faster, improves walk-away automation, and advances sample barcoding capabilities to standardize and streamline analysis for larger studies. This powerful cytometry platform with proven sensitivity, high dynamic range and the resolution to capture 50-plus targets simultaneously, including cell surface markers, signaling proteins and cytokines, supports biomarker discovery, patient stratification and treatment response monitoring.
XTra Speed
Combines up to 4x enhanced throughput with automated sample handling to expedite insights.
XTra Reproducibility
Demonstrates consistency across sample collection methods and a <9.2% CV regardless of workflow, enabling researchers to leverage large cohorts, longitudinal sampling, and multi-site collections with ease and accuracy.
XTra Compliance
Ensures secure and audit-ready data management with integrated 21 CFR Part 11 compliance-enabled software to meet relevant requirements for clinical research.
XTra Scale
Advances barcoding capabilities – a powerful method for harmonizing large datasets of more than 100 samples in a single tube, minimizing technical variability and reducing workflow burdens for clinical trials.
CyTOF XT family of systems
Whether you’re doing discovery, translational or clinical research, we have a solution to fit your laboratory requirements.
Have a CyTOF XT system? Speak to your sales representative to learn how you can upgrade it with the Enhanced Throughput (ETP) Kit.
| CyTOF XT PRO | CyTOF XT + ETP®* | CyTOF XT | |
|---|---|---|---|
| 21 CFR Part 11 Compliance | ✓ | ✓ | – |
| Enhanced throughput mode. Operating at speeds up to 4× faster than the CyTOF XT system. |
✓ | ✓ | – |
| CyTOF Software v9.2 Includes major feature upgrades that increase system automation and data analysis. Key enhancements support custom de-barcoding to advance downstream analysis of sample multiplexing and automated sample dilution to improve hands-free operation. |
✓ | ✓ | ✓ |
| Compatible with tissue imager. Maximize investment with add-on spatial proteomics capabilities.** |
✓ | ✓ | ✓ |
* Enhanced Throughput Kit
** 21 CFR Part 11 compliance feature does not apply to the tissue imager.
CyTOF® for drug development
Expand the questions you can ask and get the most from those small samples … Hear directly from CyTOF users about why they use mass cytometry for their immune profiling studies, from high-parameter needs in vaccine development to quantitative receptor analysis for drug development and immunotherapy testing.
Revealing predictive
proteomic insights
CyTOF technology has been adopted for use in over a hundred clinical trials worldwide for immune monitoring and biomarker discovery studies, as it enables researchers to reliably capture 50-plus targets simultaneously
Learn more about CyTOF XT PRO applications
A robust stain-freeze-ship workflow
CyTOF XT PRO demonstrates consistency across a variety of sample collection methods:
- Fresh-stain
- Stain-preserve
- Preserve-stain
- Frozen antibody cocktails
We have much more to share about the CyTOF XT PRO
Read about applications, workflow, proprietary technology
and hear from researchers using our new CyTOF XT PRO technology
For Research Use Only. Not for use in diagnostic procedures. Patent and License Information: www.standardbio.com/legal/notices. Trademarks: www.standardbio.com/legal/trademarks. Any other trademarks are the sole property of their respective owners. ©2025 Standard BioTools Inc. All rights reserved.