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Spatial proteomic services with the Hyperion XTi Imaging System

Deeply characterize the tissue microenvironment at subcellular resolution with our Hyperion™ XTi Imaging System. Powered by Imaging Mass Cytometry™ (IMC™) technology, the Hyperion XTi Imaging System has the widest dynamic range and highest multiplexing available, enabling detailed mapping of protein organization within tissue. These services help you understand cellular function, disease mechanisms and the spatial dynamics of complex biological systems.

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Key Features Description
High-parameter analysis Detect 40-plus markers simultaneously in any tissue type without autofluorescence interference
Protein and RNA co-detection Correlate spatial protein expression with transcriptional signatures in the same tissue section
Wide dynamic range Detect both high- and low-abundance targets in a single experiment
Ready-to-go panels Choose from 20-plus pre-optimized, application-specific panels for rapid project startup
Custom panels Select from 800-plus pre-labeled antibodies; custom conjugation is also available

Services workflow

We support you from sample collection to data delivery:

  1. Section tissue or tissue microarray onto a slide.
  2. Stain slides with one antibody cocktail from Standard BioTools.
  3. Ship FFPE slides at room temperature to our Services Lab.
  4. Multiplexed acquisition of selected regions of interest or entire tissue using IMC technology
  5. Receive data, including spatial data analytics.

Compatible sample types

  • Human – fixed or frozen samples
  • Mouse – fixed or frozen samples
  • Whole tissue sections, tissue microarrays (TMAs)
  • Tissue can be pre-stained by you prior to shipping or stained by us

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High-resolution IMC images

These figures illustrate the detailed tissue imaging capabilities of Hyperion systems, revealing spatial biology with exceptional clarity.